Surgalign has been granted a patent for a surgical method using soft tissue implants obtained from xenograft sources. The process involves treating bovine dermis with specific solutions to sterilize and strengthen the implants for superior structural integrity. GlobalData’s report on Surgalign gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Surgalign, Prosthetic cardiac valves was a key innovation area identified from patents. Surgalign's grant share as of February 2024 was 60%. Grant share is based on the ratio of number of grants to total number of patents.

Sterilization and strengthening of xenograft soft tissue implants

Source: United States Patent and Trademark Office (USPTO). Credit: Surgalign Holdings Inc

A recently granted patent (Publication Number: US11883437B2) outlines a surgical method for utilizing a graft in the treatment of human patients, particularly in hernia surgery or abdominal repair. The method involves preparing the graft using a bovine dermis with a native dermal matrix. The preparation process includes treating the dermis with specific solutions such as an aqueous alkaline sodium sulfide solution, saline solution, and aqueous hydrogen peroxide solution. Dehydration of the dermis is also a crucial step, involving solvent dehydration with organic solvents like acetone or ethanol. Importantly, the graft is maintained non-crosslinked to preserve the histoarchitecture of the native dermal matrix.

Furthermore, the patent details various specific steps and parameters involved in the preparation of the graft, such as the duration of treatment with solutions, volume ratios, concentrations of salts and hydrogen peroxide, and dehydration processes. The graft can be shaped into predetermined forms through punching, stamping, or cutting, with options ranging from standard shapes like squares or circles to more customized or anatomical shapes. The method aims to provide a well-prepared graft that can be effectively used in surgical procedures, ensuring the integrity of the dermal matrix while offering versatility in shaping for different surgical needs. This patented method offers a detailed and structured approach to graft preparation, particularly beneficial in hernia surgeries and abdominal repairs, where the quality and compatibility of the graft material are crucial for successful outcomes.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.