Hologic. has filed a patent for an apparatus designed for nucleic acid amplification reactions. The device includes a receptacle holder with multiple wells, optical fibers for signal transmission, and a movable cover. The method involves applying forces to the receptacle and optical fiber for efficient operation. GlobalData’s report on Hologic gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Hologic, Image segmentation techniques was a key innovation area identified from patents. Hologic's grant share as of January 2024 was 58%. Grant share is based on the ratio of number of grants to total number of patents.

Apparatus for nucleic acid amplification reactions with optical fibers

Source: United States Patent and Trademark Office (USPTO). Credit: Hologic Inc

The patent application (Publication Number: US20240035079A1) describes a method involving a receptacle holder with receptacle wells and through holes extending from the inner surface of each well to the outer surface of the holder. The method includes providing receptacles to the wells, applying forces to the top and bottom ends of the receptacles, and contacting the bottom end with an optical fiber. The second force applied to the bottom end is specified to be less than the first force, ensuring proper handling and alignment during the process.

Furthermore, the method involves adding a reaction mixture to the receptacle, closing it with a cap, and potentially transmitting signals through the optical fiber for excitation and emission detection. Altering the temperature of the receptacle holder is also part of the method, achieved by applying a current across a thermal element. The process includes using a receptacle transport mechanism like a pipettor and a stripper plate for transferring and removing receptacles. The method also details the movement of the optical fiber within the through hole in coordination with the cover's position, ensuring precise contact between the fiber and the receptacle. Additionally, the patent application describes the use of resilient elements to facilitate the contact between the optical fiber and the receptacle, enhancing the overall efficiency and accuracy of the method.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies