Repligen has been granted a patent for a fluid filtration assembly that includes a filter housing, filter element, and two pumps for inducing alternating tangential flow of fluid. The assembly is designed for use with a fluid storage vessel, such as a bioreactor. GlobalData’s report on Repligen gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Repligen, rtRNA virus peptides was a key innovation area identified from patents. Repligen's grant share as of January 2024 was 43%. Grant share is based on the ratio of number of grants to total number of patents.

Fluid filtration assembly with alternating tangential flow for bioreactors

Source: United States Patent and Trademark Office (USPTO). Credit: Repligen Corp

The granted patent (Publication Number: US11865478B2) discloses a fluid filtration assembly comprising a fluid storage vessel, a filter housing with a filter element, and two pumps - one at each end of the filter housing. The first pump is in fluid communication with the first end of the filter housing and the fluid storage vessel, pumping fluid through the filter element in one direction, while the second pump does the same in the opposite direction. Importantly, the first and second pumps are separately controllable, allowing for precise control over the filtration process.

Furthermore, the patent details variations in the design of the fluid filtration assembly, including the type of pumps used (diaphragm or plunger pumps), the use of a hollow fiber filter element, and the ability to generate alternating tangential flow within the filter housing. The assembly also includes a controller, such as a processor, programmed to control the operation of the pumps, enabling synchronization of vacuum and pressure strokes for optimal filtration efficiency. Overall, the patent highlights the innovative features and flexibility of the fluid filtration assembly in efficiently filtering fluids in various processes.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.